Li Gene Alterations in Keratocystic Odontogenic Tumors
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منابع مشابه
Bioinformatics Analysis Reveals Genes Involved in the Pathogenesis of Ameloblastoma and Keratocystic Odontogenic Tumor
Pathogenesis of odontogenic tumors is not well known. It is important to identify genetic deregulations and molecular alterations. This study aimed to investigate, through bioinformatic analysis, the possible genes involved in the pathogenesis of ameloblastoma (AM) and keratocystic odontogenic tumor (KCOT). Genes involved in the pathogenesis of AM and KCOT were identified in GeneCards. Gene lis...
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p53 and PCNA expression in keratocystic odontogenic tumors compared with selected odontogenic cysts Summary: The aim of this study was to evaluate p53 and PCNA expression in different odontogenic lesions regarding their different clinical behaviors. Slices prepared from 94 paraffin-embedded tissue blocks (25 radicular cysts (RC), 23 dentigerous cysts (DC), 23 keratocystic odontogenic tumors (KC...
متن کاملSmoothened gene alterations in keratocystic odontogenic tumors
BACKGROUND It has been widely demonstrated that the hedgehog pathway is strongly associated with basal cell carcinoma of the skin (NBCCS). To assess potential DNA alterations related to keratocystic odontogenic tumors (KCOTs), we sequenced smoothened (SMO) genes in 12 sporadic KCOTs. METHODS Polymerase chain reaction (PCR), capillary electrophoresis and dideoxy chain-termination sequencing we...
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BACKGROUND The aims of this study were to investigate the immunolocalization of ezrin and its relationship with the podoplanin expression in keratocystic odontogenic tumors. MATERIAL AND METHODS The immunohistochemical expressions of ezrin and podoplanin by odontogenic epithelium were evaluated in keratocystic odontogenic tumors using monoclonal antibodies. RESULTS Our results showed strong...
متن کاملThe Evaluation of Diagnostic Values of RelatedMarkers in Keratocystic Odontogenic Tumor’s Angiogenesis
Introduction: Odontogenic tumors include a variety of lesions that are classified from hamartomas to benign and malignant neoplasms. Angiogenesis process helps neoplastic tissue to gain an adequate supply of oxygen and also to remove the waste products. Mean Vessel Density (MVD) evaluation is a common method for assessing angiogenesis by using different markers. To the best of our knowledge, t...
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